GIEßEN, GERMANY

Daniele De
Gregorio

Systems Engineer | Physicist | Advanced Technology Enthusiast

I am interested in advanced technologies that help improve the future of humanity.

Professional headshot of Daniele De Gregorio, Systems Engineer and Physicist
Open to opportunities
WHO I AM

A physicist who builds precision systems at the edge of what’s measurable.

I am a Systems Engineer at KLA developing and calibrating complex electron-beam metrology tools that deliver nanometer-scale precision for the world’s most advanced semiconductor processes. My work sits at the intersection of hardware, software, statistical analysis, and fundamental physics.

Before KLA I completed my Master’s in Physics at LMU Munich’s Nano-Institute, where I used machine learning for the inverse design of achromatic metalenses and fabricated chiral metamaterials integrated with perovskite nanocrystals — work that was published in ACS Photonics. My foundation in experimental particle physics (LHC collision simulation and interpolation techniques) gives me a rare ability to move fluidly between deep theoretical models and real-world production systems.

I believe the most powerful technologies are those grounded in rigorous physics and built to serve humanity’s long-term progress.

PROFESSIONAL EXPERIENCE

Experience

KLA logo
2022 — PRESENT

Systems Engineer

• KLA
One of the world’s leading providers of metrology and inspection solutions for the semiconductor industry

I am responsible for maintaining and continuously developing a complex electron-beam-based metrology system used in high-volume semiconductor manufacturing.

  • Write calibrations and monitoring scripts that track tool behavior and performance at the nanometer scale
  • Collaborate daily with cross-functional hardware, software, and process teams on tool modifications and upgrades
  • Support customer demos that showcase sub-nanometer measurement capability to prospective clients
  • Apply advanced statistical and analytical methods to isolate root causes within complex multi-physics subsystems
  • Operate confidently in the nm regime, requiring deep understanding of electron optics, vacuum systems, detectors, and stage dynamics
ACADEMIC FOUNDATION

Education & Research

M.Sc. Physics — LMU Munich (Nano-Institute)

2018 — 2021
Machine Learning for Inverse Design of Achromatic Metalenses

Designed ultrathin metalenses using machine learning to achieve achromatic performance across broad wavelength ranges. Metalenses leverage semiconductor-derived nanofabrication techniques to replace bulky conventional optics.

Read master thesis (PDF)
Chiral Metamaterials + Perovskite Nanocrystals (Published)

Fabricated chiral silicon nanoantenna arrays using electron-beam lithography, chemical vapor deposition, and plasma etching. Deposited perovskite nanocrystal monolayers and demonstrated strong polarization-dependent two-photon photoluminescence enhancement.

Read ACS Photonics paper (2022)
TEACHING ASSISTANCE

Supervised four semesters of lab courses for physics, medicine, and dentistry students. Discovered a passion for teaching and mentoring.

WARR ROCKETRY (TUM)

Contributed Python automation and propellant grain moulding to a 5 m hybrid-fuel student rocket project across mechanical, aerospace, and CS disciplines.

B.Sc. Physics — LMU Munich

2015 — 2018
Bachelor Thesis: Experimental Particle Physics

“Studies of Interpolation Techniques in the Parameter Space of Signal Models for (BSM/SUSY) Searches” at the LHC. Investigated whether computationally expensive Monte Carlo collision simulations could be replaced by intelligent interpolation between existing signal points — a direct precursor to modern surrogate modeling techniques.

Read bachelor thesis (PDF)
EXPERTISE

Skills & Competencies

Semiconductor Metrology
Electron-beam systems nm-scale calibration Inspection tools Hardware integration
Nanophotonics & Fabrication
Electron-beam lithography CVD & plasma etching Chiral metamaterials Perovskite integration Metalenses
ML for Photonics
Inverse design Achromatic metalenses Surrogate modeling Optimization
Statistical Analysis
Root-cause analysis nm-precision data Signal modeling Interpolation methods
Python & Automation
Calibration scripts Data pipelines Tool monitoring 3D-printed propellant tooling
Experimental Physics
LHC / BSM searches Monte Carlo simulation Particle detection Cross-disciplinary teams
ARTIFACTS & OUTPUT

Selected Work & Publications

M.SC. THESIS

Machine Learning for the Inverse Design of Achromatic Metalenses

LMU Munich • Nano-Institute • 2021
View PDF
PEER-REVIEWED

Strong Polarization Dependent Nonlinear Excitation of a Perovskite Nanocrystal Monolayer on a Chiral Dielectric Nanoantenna Array

ACS Photonics, 9 (11), 3506–3514 • 2022
D. De Gregorio et al.
Read on ACS Photonics
B.SC. THESIS

Studies of Interpolation Techniques in the Parameter Space of Signal Models for (BSM/SUSY) Searches

LMU Munich • Experimental Particle Physics • 2018
View PDF
LET’S CONNECT

Ready to build something extraordinary?

I’m always interested in conversations about advanced metrology, nanophotonics, deep-tech hardware, or opportunities where rigorous physics meets real engineering impact.

Get in touch